25 March 2024

The search for a cure for Alzheimer's: a future perspective

Alzheimer's is more than memory loss; it is a slowly progressing brain disorder that interferes with the reality of those affected. Despite the challenges, researchers' research maintains a hopeful outlook.

Alzheimer's versus dementia: an important distinction

Dementia is a symptom that can arise from a variety of causes, including Alzheimer's. The complexity of the condition makes developing a universal therapy challenging. A projected tripling of neurodegenerative diseases by 2050 highlights the urgency and scale of this global health crisis.

The roots of Alzheimer's: protein accumulations

Accumulations of amyloid and tau proteins in the brain are the root causes of Alzheimer's, damaging brain cells and causing neurodegeneration.

Genetic conundrums and heredity

The influence of genetics on Alzheimer's is significant, but not absolute. Although certain genetic factors increase the risk, the development of the disease is not guaranteed.

The current state of play: therapies and treatments

Despite existing treatments targeting protein accumulations, a curative treatment for Alzheimer's remains out of reach.

With a focus on immunological approaches and antibody therapies, researchers remain optimistic about the development of future treatments, acknowledging the multifaceted nature of the disease and emphasising the need for a combined treatment strategy.

Controversy and outlook: the debate over new drugs

The approval of a new Alzheimer's drug in the US sparks debate and hope, despite mixed opinions on its effectiveness and high cost. Research highlights the complexity of the disease and the importance of varied treatment strategies.