12 August 2024
Dementia is a growing global problem that affects not only individuals, but also families, communities and healthcare systems. With the Lancet Commission's recent 2024 update, it is clearer than ever that we can make a significant impact on the prevalence of this debilitating disease. The addition of new risk factors gives us the opportunity to further refine prevention and intervention strategies. Let's dig deeper into the latest findings and discover how we can prevent or delay almost half of all dementia cases worldwide.
The Lancet Standing Committee on Dementia Prevention, Intervention and Care is a global authority that continuously researches ways to prevent and manage dementia. Their 2024 update adds two new risk factors to their list of already known causes: high LDL cholesterol and vision loss. These additions bring the total number of modifiable risk factors to 14. But what does this mean for us, and how can we use this information?
Low-density lipoprotein (LDL), often referred to as the "bad" cholesterol, has long been known as a risk factor for cardiovascular disease. However, recent research suggests that elevated LDL levels may also promote the development of dementia. LDL cholesterol may contribute to the formation of amyloid plaques in the brain, a hallmark of Alzheimer's.
Vision loss is now recognised as a risk factor for dementia. Although the exact mechanisms are still under investigation, studies suggest that reduced visual input leads to reduced cognitive stimulation and social isolation, which may increase the risk of cognitive decline.
In addition to the newly added factors, the Lancet Commission highlights the importance of addressing the following risk factors:
By proactively dealing with these factors, we can significantly reduce the risk of dementia.
Addressing these 14 risk factors is not only the responsibility of individuals, but also of society as a whole. Communities, governments and health institutions must work together to raise awareness and improve access to preventive resources and care.
The Lancet Commission's 2024 update reminds us that although dementia is a complex condition, there is huge potential to prevent or delay it through targeted actions. By being aware of and taking action on the 14 modifiable risk factors, we can make a significant impact on our lives and those of future generations.
With joint efforts, we can dramatically reduce the impact of dementia on our world and create a healthier future for all.